• br Thirty five patients had

  2020-03-24

  

  Thirty-five patients had positive Kainic acid nodes in the postoperative pathological report, 16 of whom were in the N1 stage and 19 in the N2 stage. During a median 13-month follow-up period (range 7–39 months), 15 patients developed cervical lymph node metastasis, and 2 patients had local re

• br Conclusion The promoter of OGDHL gene is hypermethylated

  2020-03-24

  

  Conclusion: The promoter of OGDHL gene is hypermethylated in colorectal cancer and might be considered as a biomarker for its development. Keywords: Colorectal cancer; Oxoglutarate dehydrogenase like; OGDHL; methylation; Epigenetic Introduction Colorectal cancer (CRC) is the third most co

• br II br III br Information source br

  2020-03-17

  

  II III Information source Demographic information Description of neoplasm V First course of therapy VI Follow up information VII Recoded variables Table 4 List of variables used in the experiments. r> No. Variable Description No. Variable Description 1 PUBCSNU

• using ICP MS analysis As shown in Fig a

  2020-03-17

  

  using ICP-MS analysis. As shown in Fig. 2a, the Au content of the tumor The thermal dose was calculated from the temperature profile of the increases with prolonging time after injection so that the maximum tumor during photothermal therapy using the empirical relationship concentration of A

• Sorafenib br E ectiveness of the HPV vaccine br

  2019-11-12

  

  4.1.2. Effectiveness of the HPV vaccine Many participants perceived that they lacked adequate knowledge about HPV and the HPV vaccination. Without adequate information, participants expressed uncertainty about the effectiveness of the HPV vaccine. Even participants who reported regular health car

• br Result br Patient characteristics br

  2019-11-11

  

   Result Patient characteristics Treatment delivery 98.8% of patients who completed treatment were per protocol or with an acceptable deviation. Three patients gave up treatment during radiotherapy for bacterial pneumonia (arm A), mycotic infection (arm C) and medical insurance (arm C).

• br Needle intrusions to rectum

  2019-11-11

  

  Needle intrusions to rectum or bowel were seen in 30 postprocedural scans. However, no postoperative gastroin-testinal complications such as bowel obstruction or perito-nitis were found. Previously, Lee et al. have described Grade 3e4 gastrointestinal toxicity events in patients treated with P-ISB

• br Discussion br Here we

  2019-11-05

  

  4. Discussion Here we report the results of the second phase of drug development for OTL38 NIR for the intraoperative imaging of ovarian cancer. In this prospective study, NIR imaging with OTL38 was feasible among various Table 4 False-positive lesions detected by OTL38 and investigator.

• br miR a p miR p miR

  2019-10-30

  

  miR-27a-3p, miR-143-3p, miR-144-3p, miR-148a-3p, miR-424-5p, miR-425-5p, and miR-1260b were significantly downregulated in the CRC plasma samples compared with the control samples. The AUC values of seven miRNAs were all above 0.7 with high sensitivity and specificity, which indicated good accurac

• br Identification of an ALDH A Family Specific Inhibitor

  2019-10-29

  

  Identification of an ALDH1A Family-Specific Inhibitor The observations above and the literature suggest that the ALDH1A family members could contribute to cancer stemness (Condello et al., 2014; Li et al., 2014; Raghavan et al., 2017; Yip et al., 2011). Given the differential expression of ALDH1A

• Journal of Steroid Biochemistry and Molecular Biology br

  2019-10-29

  

   Journal of Steroid Biochemistry and Molecular Biology 185 (2019) 57–70 PBS, the spheroids were first covered with 20 μl human serum, and then mixed well with 10 μl human thrombin until coagulation occurred. The Lovastatin embedded spheroids were then further processed for paraffin em-bedding an

• br means they act with higher selectivity against tumours th

  2019-10-22

  

  means they act with higher selectivity against tumours, than healthy and normal cells [30–32]. The molecular mechanism of such tissues recognition is still unknown, and probably could be with greater tu-mour tissue vascularisation explained [31]. Development of light emitted diodes and lasers for

• br Fig Apoptosis analysis by

  2019-10-22

  

  Fig. 8. Apoptosis analysis by TUNEL in MTS. A549 MTS (A) and LL2 MTS (B) were treated with PTX, PLGA-PTX and PLGA at a dose equivalent to the IC50 for 4 days (see Methods). Untreated MTS were used as controls. Apoptosis (red) was detected using a TUNEL assay. The nuclei were stained with Hoechst (

• br Methods br Miglyol N oil

  2019-10-22

  

  2. Methods Miglyol® 812 N oil – medium chain triglyceride (MCT) was kindly donated by CREMER OLEO GmbH & Co. Surfactants: Kolliphor® HS 15 (PEG-660-12 hydroxystearate) was kindly provided by BASF ChemTrade GmbH; Tween® 80- polyoxyethylene sorbitan monooleate and hexadecyltrimethylammonium bromi

• br indicated that the preferential killing effect of DN was

  2019-10-21

  

  indicated that the preferential killing effect of DN3 was associated with selective induction of both apoptosis and G2/M arrest. 3.3. DN3 damages mitochondria in intact gastric cancer cells Mitochondria play a vital role in intrinsic apoptosis signals, and the loss of MMP is required for ind

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